samir123
1 post
Sep 04, 2024
9:39 PM
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1-boc Piperazine
, BOC-PAZ, RARECHEM AR PA 0026, 1-N-BOC-PIPERAZINE, tert-butyl 1-piperazinecarboxylate, tert-butyl l-piperazinecarboxylate, N-BOC-PIPERAZINE, PIBOC, 1,1-Dimethylethyl 1-piperazinecarboxylate, t-Butyl 1-piperazincarboxylate, BOC-PIPERAZINE, piperazine-1-carboxylic acid tert-butyl ester
1-Boc Piperazine1-Boc-piperazine is a protected N-Boc piperazine. 1-Boc-piperazine is subject to Buchwald-Hartwig coupling with aryl Halides. 1-Boc-piperazine is prepared with the 80% range using N-Boc protection that is solvent-free and catalyzed by Iodine.
1-Boc piperazine is useful in the creation of (m-phenoxy)phenyl substituted piperazine derivatives. It can also be used to make the indazole inhibitors of DNA gyrase. Further, it plays an important role in the preparation of alfa,beta-poly(2-oxazoline) lipopolymers through living cationic ring opening polymerization. It is also involved in Buchwald-Hartwig coupling reactions the aryl halids.
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