Super Vilitra, which combines Vardenafil and Dapoxetine, affects the enzyme PDE5 (phosphodiesterase type 5) due to its role in treating erectile dysfunction (ED). Here's a breakdown of why and how it works:

Role of PDE5 in ED: PDE5 is an enzyme that breaks down cyclic guanosine monophosphate (cGMP), a molecule that helps relax smooth muscle cells in the penis and dilate blood vessels, leading to an erection. By inhibiting PDE5, Vardenafil helps increase cGMP levels, which improves blood flow to the penis and enhances the ability to achieve and maintain an erection.

Action of Vardenafil: Vardenafil specifically targets and inhibits PDE5, which results in increased levels of cGMP in the corpus cavernosum (the spongy tissue in the penis). This leads to prolonged and more sustained erections in response to sexual stimulation.

Combined Effect with Dapoxetine: Super Vilitra also contains Dapoxetine, which is a selective serotonin reuptake inhibitor (SSRI) used to treat premature ejaculation. While Dapoxetine doesn’t affect PDE5, its inclusion in Super Vilitra helps address both erectile dysfunction and premature ejaculation simultaneously.

In summary, Super Vilitra’s effectiveness in treating ED is largely due to Vardenafil's inhibition of PDE5, which enhances the natural erectile response and improves sexual performance.

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